BDBM50292978 CHEMBL489095::GSK-962040::N-(3-Fluorophenyl)-1-[(4-([(3S)-3-methyl-1-piperazinyl]methyl)phenyl)acetyl]-4-piperidinamine

SMILES C[C@H]1CN(Cc2ccc(CC(=O)N3CCC(CC3)Nc3cccc(F)c3)cc2)CCN1

InChI Key InChIKey=RZKDEGZIFSJVNA-IBGZPJMESA-N

Data  7 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50292978   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50292978(CHEMBL489095 | GSK-962040 | N-(3-Fluorophenyl)-1-[...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using diethoxyfluorescein substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50292978(CHEMBL489095 | GSK-962040 | N-(3-Fluorophenyl)-1-[...)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using 7BQ substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed